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June 12, 2017June 12, 2017

Synthetic Genomics, Advaxis Launch Venture to Produce Synthetic DNA for Immunotherapy Clinical Trials

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Synthetic Genomics and Advaxis have developed a current good manufacturing practice (cGMP) synthetic biology suite to produce synthetic DNA constructs. The cGMP facility meets U.S. Food and Drug Administration (FDA) requirements to ... Read more

June 7, 2017June 7, 2017

Opdivo Showing Early Promise in Advanced Cervical Cancer Patients Enrolled in Phase 1/2 Trial

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Preliminary data from a Phase 1/2 trial, presented at the American Society of Clinical Oncology Annual 2017 Annual Meeting, shows that Opdivo (nivolumab) monotherapy was effective in more than 26 ... Read more

June 5, 2017

Experimental New Device May Allow for Easier Cervical Cancer Screening

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A new device developed at Duke University aims to improve cervical cancer screening by replacing uncomfortable speculum exams and high-cost colposcopes with a device that would allow for at home ... Read more

June 2, 2017

Patients Being Recruited for Phase 2 Trial of Keytruda and Chemoradiation in Cervical Cancer

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Cervical cancer patients are being recruited for a Phase 2 clinical trial of a combination of Keytruda (pembrolizumab) and chemoradiation therapy. The randomized trial (NCT02635360) is expected to include about 88 ... Read more

May 31, 2017May 31, 2017

New Study to Assess ADXS-DUAL, Opdivo Immunotherapy Combo in Metastatic Cervical Cancer

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Advaxis and Bristol-Myers Squibb have entered a clinical collaboration to evaluate the second generation of axalimogene filolisbac, called ADXS-DUAL, in combination with Opdivo (nivolumab) in women with metastatic cervical cancer. ... Read more

May 26, 2017

Keytruda Shows Promise in People with Advanced Disease, Early Phase 2 Trial Results Show

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Merck’s Keytruda (pembrolizumab) shows promise as a treatment for advanced, previously treated cervical squamous cell cancer, according to a preliminary analysis of a Phase 2 trial. The data, which will ... Read more

May 24, 2017

Chemotherapy Plus P53 Gene Therapy May Help Treat Locally Advanced Cervical Cancer

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Locally advanced cervical cancer (LACC) may be treated with a combination of neoadjuvant chemotherapy (administered before surgery) and p53 gene therapy, according to a new clinical trial. The trial results, ... Read more

May 22, 2017May 22, 2017

Cervical Cancer Screening Device Mía, by Mel-Mont Medical, Allows HPV Sampling at Home

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A new diagnostic system by Mel-Mont Medical that allows women to collect cervical cell samples at home could help boost cervical cancer screening in areas where women lack access to health services. ... Read more

May 19, 2017

Cervical Cancer Patient Achieves Long-lasting Response to AXAL in Clinical Trial

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One of nine cervical cancer patients treated with AXAL achieved a long-lasting partial response to the therapy, according to a Phase 1 study. The treatment’s maker, Advaxis, presented the results in a ... Read more

May 17, 2017

2 Doses of HPV Vaccine Protect Against Genital Warts, Study Finds, But Impact on Cancer Unknown

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Two doses of the human papillomavirus (HPV) vaccine are enough to protect children, younger than 15, from genital warts. The study — which looked at nearly 400,000 girls in the ... Read more